Current Members
Professor Liu Xuewei
Division of Chemistry and Biological Chemistry
School of Physical & Mathematical Sciences, College of Science
Nanyang Technological University
E-mail: xuewei@ntu.edu.sg
Office: SPMS-CBC-05-02; Telephone: (65) 6316 8901
Academic Qualifications
2000 PhD in Chemistry University of Southern California
1996 BSc, MSc in Chemistry China Agricultural University
Professional Qualifications\Memberships
2012-Present Steering Committee Member Asian Communications of Glycobiology and Glycobiotechnology (ACGG)
2004-Present Member American Chemical Society
Summary of Working Experiences
Sept 2019-Present Full Professor School of Physical and Mathematical Sciences, College of Science, NTU
Jan 2016-Present Deputy Director Centre for Antimicrobial Bioengineering, NTU
Sept 2012-Aug 2019 Associate Professor School of Physical and Mathematical Sciences, College of Science, NTU
Nov 2005-Aug 2012 Assistant Professor School of Physical and Mathematical Sciences, College of Science, NTU
Sept 2003-Oct 2005 Postdoc California Institute of Technology, Pasadena
Jun 2002-Aug 2003 Senior Research Scientist Chugai Pharma USA, San Diego
Dec 2000-Jun 2002 Research Scientist Proctor & Gamble Pharmaceuticals, Cincinnati
RESEARCH SUMMARY
Key Areas of Research
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Carbohydrate Chemistry
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Chemical Glycobiology
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Natural Products, Food Chemistry and Medicinal Chemistry
Academic Honors and Awards
2021 Fellow of Royal Society of Chemistry (FRSC)
1999 Liang Fellowship, University of Southern California
1998 President Research Fellowship, Nagoya University, Japan
1995 Zhenxing Nongyao Award, Chinese Association of Agrochemicals
1993 President Award, China Agricultural University
Research Awards / Recognition
2019 College of Science Collaborative Research Awards
2016 First Place Award, The 2nd NTU-ICES (A*STAR) Joint Science Program
2012 The 7th Asian Core Program (ACP) Lectureship Award (China)
2012 CoS Collaborative Research Award
2011 The 6th Asian Core Program (ACP) Lectureship Award (Korea)
2011 The 6th Asian Core Program (ACP) Lectureship Award (Taiwan)
2009 Young Researcher Award, School of Physical and Mathematical Sciences
Plenary / Keynote / Award / Invited Presentations [Total: 89, Last 3 years: 17]
* Partially sponsored by the organizer ** Fully sponsored by the organizer
Plenary Presentations
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**Plenary speaker, “A user-friendly glycosyl donor for glycosidic bond construction”, 中国化学会第三届全国糖化学会, Nanchang, China, 12-14 May, 2023.
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**Plenary speaker, “Synthetic Biohybrid Peptidoglycan Oligomers Enable Pan-bacteria-specific Metabolic Labeling and Active Targeting”, 中国化学会第三届全国糖化学会, Baoding, China, 21-22 September, 2019.
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**Plenary speaker, “Tailor-made Peptidoglycans and Glycoconjugates for Antimicrobial Research”, The Joint Meeting of 11th International Symposium on Integrated Synthesis (ISONIS-11) and 3rd International Symposium on Middle Molecular Strategy (3rd ISMMS), Awaji Island, Japan, 16-18 November, 2017.
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**Plenary speaker (大会特邀嘉宾), “Synthesis of Antimicrobial Peptides, Glycopeptides and Peptidoglycans”, The 1st Symposium of Carbohydrate Synthesis (首届糖合成化学高峰论坛), Jinan, China, 15-16 May, 2017.
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*Plenary speaker, “New Glycosylation Methods and New Glycosylated Nanodevices Interfacing with Living Cells”, The 15th Tetrahedron Symposium Asia, Singapore Expo, Singapore, 28-31 October, 2014.
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**Plenary speaker, “Efficient Synthesis of Oligosaccharides and Biosensors based on Carbohydrate-Lectin Interactions”, Symposium on Glycobiology & Glycobiotechnology, Xi-An, China, 16-19 July, 2014.
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**Plenary speaker, “Glycosciences: From Synthetic Methods to Glycobiology”, Gordon Conference, Mt Snow, Vermont, USA, June 16-21, 2013.
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**Plenary speaker, “Carbohydrate-Lectin Interaction in Glycoscience”, 7th Glycan Forum, Berlin, Germany, 20-22 March, 2013.
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**Plenary speaker, “Stereoselective Synthesis of Carbohydrates and Natural Products via Facial Control”, 12th International Symposium for Chinese Organic Chemists (ISCOC) and 9th International Symposium for Chinese Organic Chemists (ISCIC), Lanzhou, China, 19–22 August, 2012.
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**Plenary speaker, “Design and Synthesis of New Therapeutic Agents for Cancers”, Combinatorial Chemistry and Chemical Biology toward A New Paradigm for Drug Discovery (CCCB), and 28th Conference on Combinatorial Chemistry (JCCF28), Osaka, Japan, 24-25 September, 2009.
Keynote Presentations
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*Keynote speaker, “Synthetic Peptidoglycans that Regulate Bacterial Cell Wall Biogenesis”, The 2nd China-Singapore Collaborative Synthetic Chemistry Symposium (CS3-2), Hangzhou, China, 11-12 May 2024.
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*Keynote speaker, “Tailor-made Peptidoglycans for Antimicrobial Research”, The 8th Asia-Pacific Conference on Ionic Liquids and Green Processes (APCIL-8), Biomedicine and Life Health Session, Kaifeng, China, 11-14 May 2024.
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*Keynote speaker, “Glycobiology-driven Carbohydrate Synthesis: A Case Study”, 糖化学研究前沿学术交流研讨会, Hebei University, Baoding, China, 13 April 2024.
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*Keynote speaker, “Tailor-made Peptidoglycans for Antimicrobial Research”, The 16th Eurasia Conference on Chemical Sciences, Bangkok, Thailand, 13-15 Dec 2023.
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*Keynote speaker, “Tailor-made Peptidoglycans for Antimicrobial Research”, Keio International Symposium on Glycoscience: Innovative Synthesis and Chemical Biology, Tokyo, Japan, 28 Feb 2023.
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*Keynote speaker, “Dual native chemical ligation for the synthesis of naturally modified protein”, Pacifichem2021 Honolulu/online December 16-21, 2021.
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*Keynote speaker, “Synthetic Biohybrid Peptidoglycan Oligomers Enable Pan-bacteria-specific Metabolic Labeling and Active Targeting”, 7th International Symposium on Middle Molecular Strategy (ISMMS-7), Kobe and online, 15 October, 2021.
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*Keynote speaker, “Exploring and Exploiting Carbohydrate-Lectin Interactions in Biomedical Context: Nano Approaches”, Asian Carbohydrate Chemistry and Glycobiology Webinar, online, 21 May, 2021.
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*Keynote speaker, “Synthetic Biohybrid Peptidoglycan Oligomers Enable Pan-bacteria-specific Metabolic Labeling and Active Targeting”, The 18th Asian Chemical Congress, Taipei, Taiwan, 8-12 December, 2019.
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*Keynote speaker, “Engineering Bacterial Cell Wall with Synthetic Peptidoglycans”, The 11th Asian Community of Glycoscience and Glycotechnology (ACGG) Conference, Busan, Korea, 11-14, November, 2019.
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**Keynote speaker, “Simplicity in Complexity: Advanced Glycosylation for Carbohydrate and Glycoconjugate Synthesis”, 第21 届中国科协年会——海峡两岸暨港澳绿色发展青年论坛, Harbin, China, 28 June – 1 July, 2019.
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*Keynote speaker, “Glycosciences: The Next Biomolecular Frontiers”, ANNUM VI (Asian network for natural and unnatural materials) conference, Gifu, Japan, 27-28 July 2018.
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*Keynote speaker, “Dual Glycosylation: A Minimalist Approach for Oligosaccharide Synthesis”, The 29th International Carbohydrate Symposium, Lisbon, Portugal, 15-19th July, 2018.
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**Keynote speaker, “Advanced Glycosylation Methods That Allows Easy Access to Complex Glycoconjugates”, Synthetic Biology International Meeting, Wuhan, China, 21-22 May, 2018.
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*Keynote speaker, “Tailor-made Peptidoglycans and Glycoconjugates for Antimicrobial Research”, 1st National Conference of Signal Communication and Pathogenesis in Microbes, Guangzhou, China, 1-4 December, 2017.
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*Keynote speaker, “Antimicrobial Peptides, Glycopeptides and Peptidoglycans”, The 3rd Glycobiology World Congress, London, UK, 26-28 Jun 2017.
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*Co-Chair and Keynote speaker, “Synthesis of Antimicrobial Peptides, Glycopeptides and Peptidoglycans”, International Conference on Cellular & Molecular Bioengineering (ICCMB4), Singapore, 4-6 January, 2017.
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*Session chair and Keynote speaker, “Quick Assembly of Glycosides and Glycoproteins: General Tactics and New Glycosylation Methods”, The XXVIII International carbohydrate symposium, New Orleans, USA, 17-22 July, 2016.
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*Keynote speaker, “Exploring and Exploiting Carbohydrate-lectin Interactions”, PacifiChem, Honolulu, Hawaii, USA, 15-20 December, 2015.
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**Keynote speaker, “Acceptor-controlled Stereoselective Glycosylation”, The 1st Symposium of Carbohydrate Synthesis (首届糖合成化学高峰论坛), Nanchang, China, 10-11 April, 2015.
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*Session chair and Keynote speaker, “New Glycosylation Methods & New Glycosylated Nanodevice Interfacing with Living Cells”, Society for Glycobiology (SFG) & Japanese Society of Carbohydrate Research (JSCR) Joint Meeting, Honolulu, Hawaii, USA, 16-19 November, 2014.
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*Keynote speaker, “Glycosciences: From Synthetic Methods to Glycobiology”, Singapore – South Korea Symposium on Glycomics, BioProcessing Institute, A*STAR, Singapore, 13 February, 2014.
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*Keynote speaker, “Stereoselective Glycosylation and Its Use in the Synthesis of Carbohydrates and Natural Products”, 26th International Carbohydrate Symposium, Madrid, Spain, 22-27 July, 2012.
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*Keynote speaker, “Stereoselective Glycosylation and Its Use in the Synthesis of Carbohydrates and Natural Products”, 27th Chinese Chemical Society Conference, Xiamen, China, 19-23 June, 2010.
Lectureship Award Presentations
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*Zashikai Lectureship, “Biohybrid peptidoglycan oligomers that incorporate into bacterial cell walls”, Tokyo University, Tokyo, Japan, 1 Mar 2023.
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**Award speaker, Asian Core Program Lectureship Award (2012) Tour: “Glycosciences: From Syn-thetic Methods to Glycobiology”, School of Chemistry and Chemical Engineering, Beijing University, China, 9 September, 2013.
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**Award speaker, Asian Core Program Lectureship Award (2012) Tour: “Glycosciences: From Syn-thetic Methods to Glycobiology”, School of Pharmacy, Beijing University, China, 11 Sept., 2013.
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**Award speaker, Asian Core Program Lectureship Award (2012) Tour: “Glycosciences: From Syn-thetic Methods to Glycobiology”, Institute of Chemistry, Chinese Academy of Sciences, China, 12 September, 2013.
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**Award speaker, Asian Core Program Lectureship Award (2011) Tour: “Glycosciences: From Syn-thetic Methods to Glycobiology”, KAIST, Korea, 5 Aug, 2013.
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**Award speaker, Asian Core Program Lectureship Award (2011) Tour: “Glycosciences: From Syn-thetic Methods to Glycobiology”, POSTECH, Korea, 6 Aug, 2013.
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**Award speaker, Asian Core Program Lectureship Award (2011) Tour: “Glycosciences: From Syn-thetic Methods to Glycobiology”, Sungkyunkyan University, Suwon, Korea, 8 August, 2013.
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**Award speaker, Asian Core Program Lectureship Award (2011) Tour: “Glycosciences: From Syn-thetic Methods to Glycobiology”, National Taiwan Normal University, Taiwan, 14, May, 2013.
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**Award speaker, Asian Core Program Lectureship Award (2011) Tour: “Glycosciences: From Syn-thetic Methods to Glycobiology”, National Tsing Hua University, Taiwan, 15 May, 2013.
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**Award speaker, Asian Core Program Lectureship Award (2011) Tour: “Glycosciences: From Syn-thetic Methods to Glycobiology”, National Chiao Tung University, Taiwan, 16 May, 2013.
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**Award speaker, Asian Core Program Lectureship Award (2011) Tour: “Glycosciences: From Syn-thetic Methods to Glycobiology”, National Sun Yat Sen University, Taiwan, 17 May, 2013.
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**Award speaker, Asian Core Program Lectureship Award (2006) Tour: “An Easy Access to Amino-glycosides via Intramolecular Rh-catalyzed Aziridination of Glycals”, Keio University, Tokyo, Japan, 23 June, 2008.
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**Award speaker, Asian Core Program Lectureship Award (2006) Tour: “An Easy Access to Amino-glycosides via Intramolecular Rh-catalyzed Aziridination of Glycals”, Tokyo Institute of Technology, Tokyo, Japan, 24 June, 2008.
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**Award speaker, Asian Core Program Lectureship Award (2006) Tour: “An Easy Access to Amino-glycosides via Intramolecular Rh-catalyzed Aziridination of Glycals”, The University of Tokyo, Japan, 25 June, 2008.
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**Award speaker, Asian Core Program Lectureship Award (2006) Tour: “An Easy Access to Aminoglycosides via Intramolecular Rh-catalyzed Aziridination of Glycals”, RIKEN, Tokyo, Japan, 27 June, 2008.
Invited Presentations
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*Invited speaker, “Glycobiology-driven Carbohydrate Synthesis: A Case Study”, Shanghai Institute of Materia Medica, Shanghai, China, 16 April 2024.
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*Invited speaker, “Glycobiology-driven Carbohydrate Synthesis: A Case Study”, East China University of Science and Technology, Shanghai, China, 15 April 2024.
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*Invited speaker, “Oligosaccharide Synthesis Enabled by Catalytic Strain-Release Glycosylation”, the 16th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-16), Singapore, 1-4 December, 2023.
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*Invited speaker, “Tailor-made Peptidoglycans for Antimicrobial Research”, Shandong University, 前沿交叉青岛研究院, Qingdao, China, 26 May 2023
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*Invited speaker, “Rapid Access to Bacterial Cell Wall Feedstocks and Related Studies”, Shandong University, NGRC, Qingdao, China, 24 May 2023.
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*Invited speaker, “Tailor-made Peptidoglycans for Antimicrobial Research”, Tokyo Institute of Technology, Tokyo, Japan, 2 Mar 2023.
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*Invited speaker, “Tailor-made Peptidoglycans for Antimicrobial Research”, Jiangxi Normal University, Nancang, China, 9 December 2022.
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*Invited speaker, “Exploring and Exploiting Carbohydrate-Lectin Interactions in Biomedical Context”, Ocean University of China, Qingdao, China, 13 January 2022.
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*Invited speaker, “Exploring and Exploiting Carbohydrate-Lectin Interactions in Biomedical Context”, Shandong University, Qingdao, China, 12 January 2022.
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*Invited speaker, “Exploring and Exploiting Carbohydrate-Lectin Interactions in Biomedical Context: Nano Approaches”, Northwestern Polytechnical University, Xi An, China, 28 December 2021.
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*Invited speaker, “Glycosciences: From Synthetic Methods To Glycobiology”, Institute for Advanced Studies, University of Cergy-Pontoise, France, 16-23 December, 2019.
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*Invited speaker, “Exploring and Exploiting Carbohydrate-Lectin Interactions in Biomedical Context: Nano Approaches”, ICMAT 2019, Marina Bay Sands, Singapore, 23-28 June, 2019.
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*Invited speaker, “Biohybrid peptidoglycan oligomers that incorporate into bacterial cell walls”, The 11th International Symposium on Glycosyltransferases, Qingdao, China, 19-23 June, 2018.
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**Invited speaker, “Glycosciences: The Next Biomolecular Frontiers”, Northwest University, Xi-An, China, 4 May, 2018.
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**Invited speaker, “Glycosciences: The Next Biomolecular Frontiers”, Northwest A&F University, Shanxi, China, 2 May, 2018.
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**Invited speaker, “Strategic Glycosylations”, Osaka University, Osaka, Japan, 20 November, 2017.
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*Invited speaker, “Glycosylation in Carbohydrate Synthesis and Glycoprotein Synthesis”, 13th Midwest Carbohydrate and Glycobiology Symposium, Madison, WI, USA, 22-23 September, 2017.
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**Invited speaker, “Glycosciences: From Synthetic Methods to Glycobiology”, South China Agricultural University, Guangzhou, China, 18 September, 2017.
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*Invited speaker, the 14th International Symposium for Chinese Organic Chemists (ISCOC) and the 11th International Symposium for Chinese Inorganic Chemists (ISCIC), Singapore, 8-10 Dec., 2016.
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*Session chair and invited speaker, “Dual Native Chemical Ligation: New Methods for Peptide and Glycopeptide Synthesis”, P2S2 Symposium, Singapore, 8-9 Dec 2016.
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**Invited speaker, “Glycochemistry and Glycobiology”, Dalian Institute of Chemistry and Physics, Chinese Academy of Sciences, Dalian, China, 6 April, 2016.
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**Invited speaker, “Glycochemistry and Glycobiology”, Jiangnan University, Wuxi, China, 8 April, 2016.
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**Invited speaker, “Glycobiology-Oriented Synthesis”, NanjingTech University, Nanjing, China, 11 April, 2016.
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**Invited speaker, “Glycobiology-Oriented Synthesis”, Hangzhou Normal University, Hangzhou, China, 12 April, 2016.
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*Invited speaker, “Glycosciences: From Synthetic Methods to Glycobiology”, 6th ICBE-International Conference on Biomolecular Engineering, Singapore, 5-7 January, 2016.
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*Co-organiser, The 7th International Peptide Symposium, at Breakthrough Theatre, Matrix, Biopolis, Singapore, 9-11 December, 2015
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**Invited speaker, “Glycosciences: From Synthetic Methods to Glycobiology”, School of Pharmacy and School of Chemistry and Chemical Engineering, Shandong University, Jinan, China, 6 April, 2015.
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**Invited speaker, “New Glycosylation Methods and Glycobiology”, School of Pharmacy, Sichuan University, Chengdu, China, 8 April, 2015.
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**Invited speaker, “New Glycosylation Methods and Glycobiology”, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi-An, China, 16 April, 2015.
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*Invited speaker, “New Glycosylation Methods & New Glycosylated Nanodevice Interfacing with Living Cells”, 8th Singapore International Chemistry Conference, U-Town, Singapore, 14-17 December, 2014.
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*Invited speaker, “The Intriguing Dual-Directing Effect of 2-Cyanobenzyl Ether for Highly Stereospecific Glycosylation Reaction”, ICCEOCA-9/NICCEOCA-5, Petaling Jaya, Malaysia, 1-4 December, 2014.
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Invited speaker, “Novel Glycosylated Nanodevices Interfacing with Living Cells”, Singapore Sensor Centre Inaugural networking workshop, NUS, Singapore, 26 July, 2014.
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*Invited speaker, “Stereoselective Glycosylation Methods and Their Application in Oligosaccharide Synthesis”, the 5th International Conference on the Development of Biomedical Engineering, Ho Chi Minh City, Vietnam,16-18 June, 2014.
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*Invited speaker, “Stereoselective Glycosylation and Its Use in the Synthesis of Carbohydrates and Natural Products”, 2014 Canadian Society for Chemistry (CSC) annual conference, Vancouver, Canada, 1-5 June, 2014.
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*Invited speaker, “Interfacing Glycosylated Nanodevice with Living Cells: From Biosensing to Drug Delivery”. the Asia-Canada Glycoscience Symposium, Vancouver, Canada, 31 May-1 June, 2014
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**Invited speaker, “Glycosciences: From Synthetic Methods to Glycobiology”, Huazhong University of Science and Technology, School of Chemistry and Chemical Engineering, Wuhan, China, 21 April, 2014.
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**Invited speaker, “Glycosciences: From Synthetic Methods to Glycobiology”, School of Pharmacy, Huazhong University of Science and Technology, Wuhan, China, April 22, 2014.
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**Invited speaker, “Glycosciences: From Synthetic Methods to Glycobiology”, School of Chemistry, Huazhong Agricultural University, Wuhan, China, 23 April, 2014.
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**Invited speaker, “Glycosciences: From Synthetic Methods to Glycobiology”, Wuhan University of Technology, Wuhan, China, 24 April, 2014.
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Invited speaker, “New Glycosylation Methods”, 27th International Carbohydrate Symposium, Bangalore, India, 12-17 January, 2014.
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**Invited speaker, “Design and Synthesis of New Therapeutic Agents for Cancers”, Shandong University, China, 2-5 September, 2013.
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**Invited speaker, “Carbohydrates – The Next Biomolecular Frontiers”, Southwest University, Chongqing, China, 2 July, 2013.
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**Invited speaker, “New Methods for Carbohydrate Synthesis”, Yunnan University, Kunming, China, 19-22 June, 2012.
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*Invited speaker, “Stereoselective Glycosylation and Its Use in the Synthesis of Carbohydrates and Natural Products”, 28th Chinese Chemical Society Conference, Chengdu, China, 13-16 April, 2012.
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*Invited speaker, “New Synthetic Methods in Carbohydrate Chemistry”, Zhejiang Normal University, Hangzhou, China, 11 April, 2012.
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*Invited speaker, “Direct and stereoselective synthesis of a-Linked 1,3-cis-3-aminodeoxyglycosides”, The 6th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-6), Hong Kong, 11-15 December, 2011.
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**Invited speaker, “Discovery of Estrogen Receptor Antagonist: Protein-ligand Binding Study”, East China Normal University, Shanghai, China, 16-18 June, 2010.
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Invited speaker, “Design and Synthesis of New Therapeutic Agents for Cancers”, University of New South Wales, Sydney, Australia, 11-14 May, 2010.
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*Invited speaker, “Large-scale Fabrication of Wavelike Single-crystal Nanosheets for High-power Lithium Ion Batteries”, 8th International Symposium on New Materials for Electrochemical Systems, Shanghai, China, 11-15 July, 2010.
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Invited speaker, “Design and Synthesis of New Therapeutic Agents for Cancers”, NUS–UoH Chemistry Bilateral Symposium, NUS, Singapore, 14-15 December, 2009.
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Invited speaker, “Conversion of Glucose and Cellulose to DMF, a Potential Additive in Gasoline”, 1st Annual Workshop on Energy Research Organized by ERI@N and NSWU, NTU, Singapore, 6-7 August, 2009.
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Invited speaker, “Biomass-derived Gasoline Additive”, 1st Annual Workshop on Energy Research Organized by ERI@N, NTU, Singapore, 2-4 June, 2009.
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*Invited speaker, “Synthesis of Sugars and Other Neuritogenic Molecules”, 2nd UK-Singapore Symposium – Contemporary Organic Synthesis, Methods and Techniques, Biopolis, Singapore, 15 February, 2008.
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Invited speaker, “Sugars in Organic Synthesis and Chemical Biology”, International Symposium on Catalysis and Fine Chemicals 2007, Nanyang Technological University, Singapore, 17-21 December, 2007.
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*Invited speaker, “Intramolecular Rh-catalyzed Aziridination of Glycals: A Novel Direct Access to Aminoglycosides”, PERCH-CIC Congress V, Pattaya city, Thailand, 6-9 May, 2007.
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*Invited speaker, “Synthetic Study of Chondoitin Sulfate Small Molecules That Stimulate Neuronal Outgrowth”, First International Conference of Cutting-Edge Organic Chemistry, Naha-city, Okinawa, Japan, 16-20 October, 2006.
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Invited speaker, “Design and Synthesis of Peptidomimetics as MC4R Ligands”, Nanyang Technological University-University of Warwick Symposium, NTU, Singapore, 17 August, 2006.
Research Funding
External Grants [Total: S$10,331,626.15, Last 3 years: S$4,235,620.00]
Academic Community Roles
2021 - present Editorial Board, Green Synthesis and Catalysis
2017 - present Editorial Board, Journal of Clinical Chemistry and Laboratory Medicine
2017 - present Editorial Board, Journal of Transdisciplinary Biomedicine
2017 - present Section Editorial Board, Molecules
2014 - present Review Editor, Frontiers in Chemistry
2013 - present Editorial Committee Member, Journal of Chinese Pharmaceutical Sciences
2012 - present Steering Committee Member, Asian Communications of Glycobiology and Glycobiotechnology (ACGG)
Nanyang Technological University
School of Chemistry, Chemical Engineering and Biotechnology (CCEB)